Phenomenology of practice is a useful, rigorous way of deeply understanding human phenomena. Therefore, it allows research to be conducted into nursing's most sensitive and decisive aspects. While it is a widely used research approach and methodology in nursing, it is seldom addressed and made use of in its practical and applied value. This article aimed to approach the global outlook of van Manen's hermeneutic‐phenomenological method to better understand its theoretical background and to address and support the contribution this method (...) can make to nursing, if rigorously applied. For a professional discipline like nursing, van Manen's approach is especially interesting because, in addition to contributing to the body of knowledge of nursing, it provides a special kind of knowledge that allows nurses to act in a more reflective manner, and with tact and skill, in certain situations and relationships that arise in their daily practice. A more in‐depth understanding of this research methodology may help nurse‐researchers make good use of it and also harness knowledge derived from this type of research. This comes as a result of assuming that phenomenological texts, the final product of the research, have tremendous educational potential for people who read them carefully. (shrink)

Construction of the trunk/caudal region of the vertebrate embryo involves a set of distinct molecules and processes whose relationships are just coming into focus. In addition to the subdivision of the embryo into head and trunk domains, this “caudalisation” process requires the establishment and maintenance of a stem zone. This sequentially generates caudal tissues over a long period which then undergo differentiation and patterning in the extending body axis. Here we review recent studies that show that changes in the signalling (...) properties of the paraxial mesoderm act as a switch that controls onset of differentiation and pattern in the spinal cord. These findings identify distinct roles for different caudalising factors; in particular, Fibroblast Growth Factor (FGF) inhibits differentiation in the caudal stem zone, while Retinoic acid (RA) provided rostrally by somitic mesoderm is required for neuronal differentiation and establishment of ventral neural pattern. Furthermore, the mutual opposition of FGF and RA pathways controls not only neural differentiation but also mesoderm segmentation and might also underlie the progressive assignment of rostrocaudal identity by regulating Hox gene availability and activation. BioEssays 26:857–869, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

La piedra clave que sostiene el sistema simbólico de las religiones, es sin duda, la experiencia de salvación. F. Heiler afirmaba que el aroma de las religiones es la soteriología y R. Panikkar proponía definir el hecho religioso con tres simples palabras: "camino de salvación". Por ello, la realidad existencial del dolor y el sufrimiento son el gran reto lanzado a la experiencia religiosa: proponéis salvación, se puede decir a los creyentes, pero el dolor y el sufrimiento siguen existiendo. ¿Cómo (...) es posible? Por ello, todas las religiones de formas muy diferentes, responden a la pregunta por sufrimiento y proponen formas para integrarlo existencialmente. (shrink)

Solo el atrevimiento característico de la sabiduría nos impulsa a tomar el camino más complejo de pensar en el amor, pues nos hace conscientes del error de querer construir lo principal de la existencia en un sentimiento blando como la arena, incapaz de resistir cualquier contradicción de importancia. Encontrar el auténtico fundamento de esa pregunta, que en la actualidad no se puede dar por descontado, es la única manera de edificar la casa del hombre sobre roca, y apartarnos de la (...) necedad de levantar un edificio sin cimientos. Es una elección trascendental que, como el Papa Benedicto XVI ha señalado con fuerza, tiene una repercusión social de máximo relieve. (shrink)

Integrated approaches in the ethical decision-making (EDM) and practically wise decision-making literature are emerging as alternative perspectives to management theories that conceptualize decision-making in a rationalist and value-free manner. However, more dialogue between both perspectives and qualitative research that applies them is required. In addition, there is a need for empirical analysis on business engagement in the face of grand challenges in developing countries. This paper proposes an integrated practically wise EDM framework to study how Colombian councilors who, in 2013, (...) voted for or against the merger between the Colombian state-owned company UNE and the Swedish multinational Millicom interpret this decision and its public impact. Qualitative semi-structured interviews were conducted with a voluntary sample of 18 of 21 councilors. Supporters of the UNE-Millicom merger expressed open-mindedness, seeing the merger as a means to achieve justice. On the contrary, the merger’s opponents expressed circumspection, doubting that Millicom’s intentions really leaned toward justice. We conclude that practical wisdom—embodied by both supporters and detractors—fosters an understanding of EDM beyond what leaders should not do. It also includes a democratic and balanced deliberation on what leaders think they should do to promote the common good. (shrink)

At the beginning of De Visione Dei, Nicholas of Cusa puts us before an icon of the divine glance and invites us to an experimentation – initially surrounded by the metaphorical reflection – of the mystic contemplation. Working with the metaphor of the glance, the Cusano leaves us before the Creator’s look and the creature’s look. In the De Visione Dei, the divine look is creator and lover. The God’s look sees, creates and loves. This way, the present work will (...) look for to meditate on the importance of the glance, seeking in the De Visione Dei a way to relate the multiplicity of the created look with the unit of the creator look. (shrink)

SOCREAL 2010: 2nd International Workshop on Philosophy and Ethics of Social Reality. Sapporo, Japan, 2010-03-27/28. Session 4: Argumentations and Speech Acts.

Las excusas y las condiciones eximentes tienen como finalidad mitigar la responsabilidad. Este artículo propone una distinción entre excusas y eximentes basada en el tipo distintivo de juicio que cada una trata de responder. Argumento que los eximentes afectan la relevancia causal del acusado, mientras que las excusas lo justifican total o parcialmente, porque afectan al juicio evaluativo implícito en las atribuciones de responsabilidad. Esta distinción apoya una concepción de las atribuciones de responsabilidad como un proceso en dos etapas, donde (...) cada una de ellas corresponde a un tipo diferente de responsabilidad, cuya atribución está guiada por dos tareas cognitivas y argumentativas diferentes, aunque relacionadas: explicar lo que produjo una situación, y evaluar su significación moral. (shrink)

Reasons are of the wrong kind if, despite appearing of the right kind, are not able to justify nor to motivate the formation of a mental attitude. Initially, this problem was thought to apply only within the theoretical realm of reason, but Kavka's Toxin Puzzle showed that reasons of the wrong kind are also found in the practical realm. The aim of this paper is to analyze the scope of this problem, in order to determine the kind of reasons it (...) affects. I will examine two possible solutions to this problem, and I will argue that the most promising solution, proposed by Hieronymi, is based on a conception of reasons and attitudes that is too narrow. (shrink)

El artículo reconstruye el desarrollo y los giros que tuvo la idea de la selección natural de Darwin en la obra de Sir Karl Popper. Hecho esto, se presenta la nueva interpretación de Popper sobre el darwinismo como un cambio en el concepto de evolución, entendiéndolo como un proceso que mantiene la estructura explicativa básica propuesta por Darwin pero que opera no sólo en el nivel orgánico sino en distintos niveles, vinculando su concepción pluralista de la realidad. Así, se concluye (...) presentando la epistemología evolucionista popperiana como una forma de darwinismo universal. (shrink)

La philosophie tragique a eu comme lieu de naissance la pensée nietzschéenne. L'intention de Nietzsche fut d'extraire le terme du tragique du contexte du théâtre pour construire avec lui une réflexion au service de la vie. Notre intention dans cet ouvrage est de comprendre comment la pensée de Rosset suit celle de Nietzsche et à quel moment elle s'éloigne pour écrire sa propre version de la philosophie tragique. Sur ce point nous tentons de répondre : quel est l'apport de Rosset (...) à la lignée de la philosophie tragique? Ou bien quel est l'avantage de suivre une philosophie tragique sans tomber dans la simplicité de l'optimisme? On peut voir que ces questions lient complètement la philosophie et l'éthique et invitent à échapper au sens amer et fataliste qu'habituellement on concède au terme du tragique pour l'ouvrir à la célébration de la vie. Enfin, on insiste sur la question : Rosset est-il vraiment un continuateur de Nietzsche et parvient-il à resémantiser le terme de philosophie tragique pour l'enrichir et l'amplifier, pour le singulariser avec sa propre réflexion? (shrink)

Being and value, by J. Zaragüeta y Bengoechea.--The origin of man, by X. Zubiri.--Negation, by J. Gaos.--The juridical notion of the human person and the rights of man, by L. Legaz y Lacambra.--History and truth, E. Nicol.--Vital anxiety, by J. J. López Ibor.--The moralization of power through its self--imitation, by J. L. Aranguren.--The doctor-patient relationship in the general framework of interhuman relationships, by P. Laín Entralgo.--On the singular character of the historical destiny of Europe, by L. Díez del Corral.--On (...) taking things for granted, by J. Ferrater Mora.--The idea of metaphysics, by J. Marías. (shrink)

Yasha Rohwer and Emma Marris argue that we do not have a prima facie duty to preserve the genetic integrity of species. Rohwer and Marris take the duty to preserve genetic integrity as being equal...

Resumen Este texto se centra en la concepción de la Kaaba de una mujer excepcional por su relación con Dios y por su conocimiento místico (ma‘arifa), Rābi‘a al-‘Adawiyya (m. 801). Ella protagonizó el paso de la ascética a la mística en la Basora del siglo VIII y marcó una diferencia respecto a los ascetas de su tiempo: realizó el viaje al interior de sí misma y ejerció una continua introspección para buscar el profundo deseo del corazón y purificarlo. Los relatos (...) de la peregrinación a la Kaaba, la Casa o morada de Dios, se comparan a los grados de oración descritos por Teresa de Jesús en el Libro de la Vida.Palabras clave: Kaaba, mística, Rābi‘a al-‘Adawiyya, Teresa de Jesús. (shrink)

This paper raises the possibility of a female authorship for the anonymous 14th century work The Cloud of Unknowing, which academics always attribute to a man. It points out four premises: firstly the error of sexual attribution of the authorship of The Mirror of Simple Souls, maintained until 20th century; secondly, the conception of woman by the English mystical male writers Rolle and Hilton, which is not found in the writings attributed to the author of The Cloud; thirdly, the literary, (...) theological and mystical greatness of a English woman writer of 14th century, Julian of Norwich; and, finally, the scholars' considerations about the author (man for them) of The Cloud and its related treatises, which, notwithstanding, could perfectly be attributed to a woman of the fourteenth century in England. So, the conclusion invites to question the male authorship of this masterpiece, perhaps, for the first time. (shrink)

Rho proteins belong to the small GTPases superfamily. They function as molecular switches that, in response to diverse stimuli, control key signaling and structural aspects of the cell. Although early studies proposed a role for Rho GTPases in cellular transformation, this effect was underestimated due to the fact that no genetic mutations affecting Rho‐encoding genes were found in tumors. Recently, it has become evident that Rho GTPases participate in the carcinogenic process by either overexpression of some of the members of (...) the family with oncogenic activity, downmodulation of other members with suggested tumor suppressor activity, or by alteration of upstream modulators or downstream effectors. Thus, alteration of the levels of expression of different members of the family of Rho GTPases has been detected in many types of human tumors leading to a great interest in the cellular effects elicited by these oncoproteins. This essay reviews the current evidence of dysregulation of Rho signaling by overexpression in human tumors. BioEssays 27:602–613, 2005. © 2005 Wiley Periodicals, Inc. (shrink)